For years, individuals seeking next-generation regenerative treatments believed their only option was to fly overseas—to Panama, Mexico, or the Caribbean—to access procedures unavailable in the United States. That era is over.

Florida is now at the forefront of a new movement in biologic medicine—one that combines advanced technology, clinical oversight, and a supportive regulatory environment that empowers orthopedic specialists to deliver the highest standard of regenerative care right here at home.

A New Era in Florida Medicine

As of July 1, 2025, the Florida Legislature enacted Senate Bill 1768 (CS/CS/SB 1768)—a landmark update that affirms the ability of licensed physicians to provide certain advanced biologic therapies, within clinical and ethical parameters, for orthopedic, pain-management, and wound-care indications. This change reflects Florida’s commitment to responsible innovation and positions the state as one of the most forward-thinking jurisdictions in the U.S. for regenerative healthcare delivery (Holland & Knight, 2025).

At TOSM, Dr. Patrick Tyrance Jr. and his team embrace this new opportunity—bringing advanced biologic science into an environment of safety, precision, and patient-centered care.

Advanced Biologic Therapies Now Available at TOSM

1. Exosome-Based Biologic Therapy

Exosomes are nanoscale vesicles that facilitate intercellular communication—delivering proteins, RNAs, and growth factors that influence repair and inflammation modulation. Recent literature supports their therapeutic promise in musculoskeletal and cartilage applications, showing enhanced matrix deposition and improved histological scores (PubMed ID 32159464; Frontiers in Immunology, 2023). Dr. Tyrance employs rigorously sourced, physician-verified exosome formulations designed for targeted orthopedic applications—helping patients recover mobility and reduce inflammation without surgical intervention.

2. Lipogems® Micro-Fragmented Adipose Tissue

Lipogems® is a U.S. FDA-cleared system that gently processes a patient’s own fat into micro-fragmented clusters, preserving the tissue’s native microarchitecture and regenerative niche. According to the manufacturer, ‘scientific research and clinical evidence demonstrate how adipose tissue can significantly contribute to healing processes’ (Lipogems Official Site). A 2024 systematic review found significant reductions in pain (44–62%) and measurable improvements in joint function after Lipogems-derived micro-fragmented adipose tissue injections (PMC 12255012).

At TOSM, Lipogems is offered as an outpatient procedure—performed under sterile technique, ultrasound guidance, and medical supervision for rapid recovery and minimal downtime.

3. Stromal Vascular Fraction (SVF)

SVF is derived from a small sample of a patient’s own adipose (fat) tissue and processed to yield a rich population of regenerative and immune-supportive components. Peer-reviewed research demonstrates that SVF is a ‘heterogeneous cellular conglomerate providing a repository for mesenchymal and endothelial progenitor cells that support angiogenesis, repair, and homeostasis’ (World Journal of Stem Cells, 2024). A five-year clinical follow-up for knee osteoarthritis showed significantly improved pain and function scores among SVF recipients versus controls (Stem Cell Research & Therapy, 2022).

Coming soon to TOSM, SVF treatments will be performed under strict surgical-suite protocols and paired with guided rehabilitation to optimize outcomes.

Why Florida Is the New Hub for Regenerative Medicine

• Progressive Legislation: Florida’s 2025 law (SB 1768) permits trained physicians to administer biologic therapies under clear safety standards—encouraging responsible innovation while reducing the need to seek care overseas.
• Regulatory Oversight: Treatments performed within the U.S. adhere to FDA and state medical board requirements, providing transparency and patient protection that many offshore clinics cannot match.
• World-Class Practitioners: Florida’s orthopedic community includes leaders in sports medicine, biologics, and minimally invasive procedures—making it a premier medical tourism destination.
• Integrated Care: Patients flying in from other states or countries benefit from concierge coordination, post-procedure rehabilitation, and telemedicine follow-up through TOSM’s multidisciplinary network.
• Travel Appeal: South Florida combines medical excellence with hospitality infrastructure, direct international flight access, and a climate conducive to recovery and wellness.

Realistic Expectations and Responsible Innovation

While the promise of biologic medicine is substantial, responsible practitioners acknowledge that outcomes depend on patient age, tissue condition, systemic health, and compliance with rehabilitation. As summarized by a 2024 review in Frontiers in Bioengineering & Biotechnology, ‘the translation of exosome-based therapies from bench to bedside is promising but requires ongoing standardization, manufacturing oversight, and longitudinal studies’ (PMC 11068073). At TOSM, Dr. Tyrance prioritizes transparency and evidence-based care—ensuring patients understand both the potential and the limitations of each procedure.

TOSM: A Florida Center of Excellence for Biologic Healing

From professional athletes to high-performance executives and wellness-minded travelers, TOSM serves as a destination clinic for those seeking advanced orthopedic recovery through biologic science. Whether you’re flying in from another state or another continent, our concierge team coordinates every aspect—from pre-consultation review to post-treatment follow-up—so you can focus on healing.

Schedule Your Consultation

If you’re considering regenerative medicine, explore the possibility of advanced biologic therapy with a licensed orthopedic specialist in one of the most forward-looking states in America. At TOSM, Dr. Tyrance’s precision protocols combine science, safety, and innovation—right here in Florida.

Contact us to schedule your consultation and discover why you no longer need to leave the country for world-class healing.

References

1. World Journal of Stem Cells. 2024. “Stromal Vascular Fraction Therapy Review.”
2. Stem Cell Research & Therapy. 2022. “Long-term Follow-Up of Autologous SVF for Knee Osteoarthritis.”
3. PubMed ID 32159464. “Mesenchymal Stem Cell Exosomes for Cartilage Regeneration.”
4. Frontiers in Immunology. 2023. “Exosomes in Sports Medicine and Inflammation Modulation.”
5. Lipogems Official Website. 2025. https://www.lipogems.com/en/lipogems-system/lipogems/
6. PMC 12255012. 2024. “Clinical Outcomes of Micro-Fragmented Adipose Tissue Therapies.”
7. Holland & Knight. 2025. “Florida Law Expands Physician Authority for Certain Biologic Treatments (SB 1768).”
8. Frontiers in Bioengineering & Biotechnology. 2024. “Standardization of Exosome Therapies for Clinical Translation.”